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Research Associate, DNA & Strain Construction

Asimov

Asimov

Boston, MA, USA
USD 70k-75k / year + Equity
Posted on Feb 14, 2026

Location

Boston, MA - On-site

Employment Type

Full time

Location Type

On-site

Department

DNA & Strain Construction

Compensation

  • $70K – $75K

The base salary hiring range for this position is expected to be $70,000 to $75,000 annually. The base salary offered may vary based on factors such as the final candidate’s relevant knowledge, skills and experience for the role. Our total rewards package also includes the opportunity for stock options, eligibility for our 401(k) plan, annual career development stipend, medical, dental, vision, life and disability insurances. Our robust time-off policy includes flexible time-off and unlimited sick time. We will talk about compensation in our first conversation and be transparent throughout the process about which level we think is the best match for you in our organization.

Our mission at Asimov is to advance humanity's ability to design living systems, enabling biotechnologies with outsized benefit to society. We're developing a mammalian synthetic biology platform––from cells to software––to enable the design and manufacture of next-generation therapeutics.

We are looking for a highly motivated Research Associate I to join our DNA & Strain Construction (DNASC) team as a full-time employee. In this role, you will support our high-throughput molecular biology pipeline, contributing to the efficient cloning, assembly, and sequencing of DNA constructs. You will gain hands-on experience with cutting-edge molecular biology techniques, automation, and process optimization while working in a dynamic synthetic biology environment.

About the Role:

  • Perform high-throughput cloning workflows, including PCR, Gibson Assembly, and Golden Gate Assembly to construct plasmids.

  • Operate liquid handlers (e.g., Echo, Bravo, Hamilton STAR), run the MiSeq for NGS, and utilize other automation tools for NGS library preparation and molecular cloning.

  • Conduct PCR, Golden Gate or Gibson Assembly, plasmid purification, and sequencing prep to validate DNA constructs.

  • Maintain accurate sample tracking and documentation in LIMS to ensure data integrity and reproducibility.

  • Assist with large-scale plasmid preparations (LSPs) to support internal and external projects.

  • Collaborate with scientists and other RAs to troubleshoot workflows and improve efficiency.

  • Follow standard operating procedures (SOPs) and contribute to continuous process improvements.

  • This is a full-time position supporting ongoing DNASC production and development efforts.

About You:

  • B.S. in Biology, Biochemistry, Bioengineering, or a related field (recent graduates encouraged to apply).

  • Hands-on experience with molecular cloning techniques (PCR, restriction digestion, ligation, transformation, and plasmid purification).

  • Familiarity with DNA assembly methods (Golden Gate, Gibson) and bacterial culturing techniques.

  • Comfortable working in a fast-paced lab environment, following protocols, and maintaining detailed records.

  • Experience with automated liquid handlers (Echo, Bravo, Hamilton STAR) or NGS workflows is a plus.

  • Highly organized, detail-oriented, and able to work independently or as part of a team.

We're fueled by a vision to transform biological engineering into a fully-fledged engineering discipline. Should you join our team, you will grow with a constantly evolving organization and push the frontiers of synthetic biology. Company culture is key to Asimov, and ours is a culture of recombination; we believe that our mission can only be achieved by bringing together a diverse team with a mixture of backgrounds and perspectives.

Compensation Range: $70K - $75K